Orthomolecular Psychiatry

Orthomolecular approach to psychiatry is based on the use of naturally occurring substances to supplement deficiencies or imbalances in vitamins, minerals, and other essential substances in the human body. The term “orthomolecular psychiatry” was first used by the two-time Nobel prize-winning molecular biologist Linus Pauling in an article published in the journal Science in 1968.

Although the medical community has always regarded it as the non-scientific way of healing, there is a lot of scientific evidence emerging in support of orthomolecular psychiatry, in the treatment of schizophrenia, depression, bipolar disorder etc.

Other supporters of orthomolecular psychiatry around the same time as Pauling’s first paper were Abram Hoffer, Carl Curt Pfeiffer, and Humphry Osmond, all of whom treated psychiatric disorders with nutrition. In the 1950’s Abraham Hoffer was the first major practitioner of this field.

The clinical hypothesis Hoffer and his research colleagues tested in the 1950s and
the 1960s involved the use of large doses of the B-vitamin, particularly niacin, as a novel treatment for acute schizophrenia.

In the practice of orthomolecular psychiatry, high amounts of vitamins are used, not to correct a deficiency, but to alter the body’s biochemical environment. Additionally, dietary manipulation is also utilized.

Other good reads:






A more recent article:


Some places for Orthomolecular treatment:

Orthomolecular vitamin information Center: The mission of the Centre is to provide accurate, unbiased information in a non-medical setting about the properties and uses of vitamins.


Brain Bio center: Established in 2003, the Brain Bio Centre is a not-for-profit clinic that combines nutrition and health science to optimise brain health.


Pfeiffer medical center: This non-profit organization is dedicated to assisting individuals in restoring and maintaining good health and the advancement of sound nutrition and natural healing through scientific research.


Walsh Research Institute: The non-profit Walsh Research Institute is a 501(c)3 organization dedicated to unraveling the biochemistry of mental disorders.Dr. Walsh has been a pioneer in the development of advanced nutrient therapies since his collaboration with Dr. Carl Pfeiffer of Princeton, NJ in the 1980s.


Linus Pauling Institute: The Linus Pauling Institute’s mission is to promote optimal health through cutting-edge research on micronutrients and dietary supplements and trusted public outreach.The Linus Pauling Institute (LPI) was established at Oregon State University (OSU) in August 1996 under an agreement reached between its antecedent organization, the Linus Pauling Institute of Science and Medicine, and OSU. The mission of the LPI at OSU is to determine the function and role of micronutrients, phytochemicals and microconstituents of food in maintaining human health and preventing and treating disease; and to advance the knowledge in areas which were of interest to Linus Pauling through research and education.


American College for Advancement in Medicine:The American College for Advancement in Medicine (ACAM) is a non-profit alternative medicine society dedicated to educating physicians on the latest findings and emerging procedures in preventive/nutritional medicine.


International Society for Molecular Nutrition and Therapy: Located at the Molecular Cardiology Laboratory, Philipps University of Marburg, in Germany, the objectives of ISMNT are to promote nutritional research at the molecular level with respect to health and disease; to organize scientific meetings in the area of molecular nutrition including: cancer; cardiovascular diseases; immune disorders; neurosciences; nutritional abnormalities; vitamins and trace elements.












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